What is a normal troponin level. Elevated ck mb with a normal troponin does not predict 30 day adverse cardiac events in emergency department chest pain observation unit patients affiliation 1 from the departments of emergency medicine and internal medicine section of cardiovascular medicine yale university school of medicine new haven ct.
Serial ck mb levels commonly are obtained at admission to the emergency department and are repeated in 6 12 hours.
Normal ck mb and troponin levels. Sometimes the ck test may be used if a heart attack is suspected and a troponin test is not available. Results are given in measurements of nanograms per milliliter ng ml. This study was planned to investigate the specificity and sensitivity of tn i and ck mb in chf.
Total cases troponin i cpk mb iu l 8 positive negative normal range 24 iu l raised 24 iu l 5 3 3 5. Department of emergency medicine baylor school of medicine houston tx. Comparison of troponin i vs cpk mb levels in patients presenting within 6 hours of onset of chest pain.
5 25 iu l myocardial infarction. Elevated levels of creatine kinase mb ck mb and troponin i tn i have been regarded as biochemical markers of myocyte necrosis. Ck and ck mb were once the primary tests ordered to detect and monitor heart attacks but they have now been largely replaced by the troponin test which is more specific for damage to the heart.
The normal range is between 0 and 0 4 ng ml. Ck mb may be used in follow up to an elevated ck and or when the troponin test is not available. Levels should be 2x the patient s baseline.
High levels of troponin in the blood can. 46 these studies suggest that a positive troponin result alone is an independent predictor of high risk for adverse cardiac events and that therapy with lmwhs and or gp iib iiia inhibitors appears to confer the most benefit on patients with elevated cardiac troponins. However early invasive therapy did benefit the subgroup of patients with elevated troponin levels but normal ck mb levels.
The specificity of serum cardiac troponin i was 83 with a cutoff level of 0 03 ng ml which is an expected level for healthy population but it rose to 100 with a cutoff level of 0 15 ng ml which is a reference level for patients with acute myocardial infarction. Remember that ck and even ck mb are not as specific as troponin i or t to the heart. What is an elevated troponin level.