クレアチンキナーゼ ck ってなに クレアチンキナーゼ creatine kinase 以下ck の分子量は約81000で 筋型 m と言われるものと 脳型 b といわれるものの2種類があります その二つの組み合わせから 各臓器によって分布. Current reference intervals for creatine kinase ck in the general population are not accurate for professional footballers.
All isoenzymes of ck catalyze the phosphorylation of creatine to form phosphocreatine.
Creatine kinase level ck level chart. Conditions that cause damage to any of these three areas produce an elevated level of ck. Mythili seetharaman consultant rheumatologist creatine kinase ck levels are usually elevated in persons with polymyositis ranging from 5 50 times the reference range. This test measures the amount of creatine kinase ck in the blood.
We recommend a new reference interval of 64 9 u l to 1971 7 u l for ck in male professional footballers. The mean total creatine kinase level for black men was 146 5 136 9 units liter median 108 units liter the mean level for white men was 60 8 26 1 units liter median 51 units liter and the mean level for hispanic men was. The proposed reference interval agrees with the limited published studies of football players.
Ec 2 7 3 2 creatine kinase is also sometimes referred to as creatine phosphokinase creatine phosphotransferase cpk or just ck. Creatine kinase ck is an enzyme that catalyzes the reversible phosphorylation of creatine cr by adenosine triphosphate atp. High levels of ck can indicate damage or disease of the skeletal muscles heart or brain.
Creatine kinase ck also known as creatine phosphokinase cpk or phosphocreatine kinase is an enzyme ec 2 7 3 2 expressed by various tissues and cell types ck catalyses the conversion of creatine and uses adenosine triphosphate atp to create phosphocreatine pcr and adenosine diphosphate adp. Researchers from johns hopkins medicine say that ck mb levels are often elevated when there is muscle inflammation due to conditions like lupus. Health effects of high creatine kinase level 1 may be linked to lower inflammation a study with over 12 000 people found that higher ck was linked to lower hs crp which is a measure of chronic inflammation 79.
24 204 u l 0 41 3 47 µkat l or 24 00 204 00 iu l. Physiologically when muscle contracts atp is converted to adenosine diphosphate adp and. Creatine kinase ck is an enzyme found primarily in the brain skeletal muscles and heart.