Studies in horses have shown that high ck activity is seen in various neurologic conditions including equine protozoal neuritis sarcocystis neurona but that high values are neither sensitive or specific for the latter disease. Other causes of chronic kidney disease are seen in foals or young horses and include renal hypoplasia incomplete kidney development or dysplasia improper kidney development and polycystic.
Creatine kinase ck ck occurs in high levels in skeletal and cardiac muscle.
Elevated ck levels in horses. Rarely it s elevated immediately following a meal or a fight or flight response. Serum ck and ast are increased during an episode usually 1 000 u l and unlike in other forms of rhabdomyolysis subclinical episodes characterized by persistently abnormal ck levels are common. Ck is often assessed alongside ast when assessing muscle damage.
After daily exercise horses consuming the starch and bicarbonate diets had post exercise ck levels averaging almost eight times as high as horses eating the fat diet. In the horse increased levels almost always signify acute muscle damage. This value can increase fairly rapidly when horses go off feed and this is something that is unique to the horse says wilson.
If your horse is very sick glucose might be elevated because of shock or a severe body wide infection. If your horse s blood glucose is elevated testing for cushing s disease or insulin resistance might be suggested. High levels indicate that muscle damage has occurred.
Levels peak 6 12 hours following injury and can return to normal levels in 3 4 days. However in horses unlike other animals elevated levels of bilirubin often isn t serious. Elevated levels can mean unusual loss of red cells or liver dysfunction.
Creatine kinase is an enzyme that is present in all the muscles of the body. Some horses paw or roll resembling colic. Equine exertional rhabdomyolysis er also known as tying up azoturia or monday morning disease is a syndrome that damages the muscle tissue in horses.
My knowledge of horses is limited but i do know about what an elevated creatine kinase is in people and am suspecting it is similar in horses. Creatine kinase ck is a muscle enzyme that increases after exercise. It is usually due to overfeeding a horse carbohydrates and appears to have a genetic link.
Clinical signs in draft horses may include loss of muscle mass progressive weakness and recumbency.