If ck mb is elevated and the ratio of ck mb to total ck relative index is more than 2 5 3 then it is likely that the heart was damaged. Preparation for ck mb test when you have sudden chest pain try to meet your physician within 3 8 hours of the onset of the pain.
However it is used in the case of abnormal troponin level or in the case of a suspected heart attack.
Ck mb test normal range. Specimen requirement is one sst tube of blood. The upper normal limit for men is anywhere from 200 to 395 u l 3 4 6 8 ukat l and for women it s up to 207 u l 3 52 ukat l 3 4 5. Ck activity is greatest in striated muscle mm isoenzyme heart tissue mb isoenzyme and brain bb isoenzyme.
If your ck mb is elevated and the ratio of ck mb to total ck relative index is more than 2 5 3 it is indicated that the heart may be damaged. The low normal limit for both men and women is approximately 20 30 u l 0 34 0 51 ukat l. For males normal levels of creatine kinase range between 38 to 174 units per liter u l of blood.
Based on these findings ck mb should be ordered in symptomatic patients even if total ck is not elevated. Reference range is 0 5 ng ml. Brain injury due to stroke or bleeding in the brain.
Ck levels are around 70 higher in healthy african americans compared to people of european descent. Creatine kinase is an enzyme found in the heart brain skeletal muscle and other tissues. Normal ranges of creatine kinase are as follows.
Normal serum ck is predominantly the ck mm isoenzyme. If your ck mb is elevated and the ratio of ck mb to total ck relative index is below 2 5 3 it is indicated that skeletal muscles may be damaged. Serum ck concentrations are reflective of muscle mass causing males to have higher concentrations than females.
For females normal levels of creatine kinase range between 90 to 140 units per liter u l of blood. Today ck mb test is replaced by troponin assays. A high ck with a relative index below this value suggests that skeletal muscles were.
The cpk normal range for a male is between 39 308 u l while in females the cpk normal range is between 26 192 u l. Cpk test results interpretation elevated levels of cpk 1 mainly found in the brain could be indicative of the following conditions. An elevated ck mb is defined as a value that exceeds the 99 th percentile of ck mb values in a reference control group when evaluating suspected ongoing or reinfarction and the initial troponin level is high sequential samples of a more rapidly appearing biomarker such as ck mb or myoglobin may be employed to clarify the timing of the mi.